Натрийуретические пептиды - маркеры и факторы прогноза при хронической сердечной недостаточности

Авторы: Е. З. Голухова, Н. Б. Теряева, А. М. Алиева

Организация:
Научный центр сердечно-сосудистой хирургии им. А. Н. Бакулева (дир. – академик РАМН Л. А. Бокерия) РАМН, Москва

Раздел: Сердечная недостаточность

Библиографическая ссылка: Креативная кардиология. 2007; (): -

Цитировать как: Е. З. Голухова, Н. Б. Теряева, А. М. Алиева. Натрийуретические пептиды - маркеры и факторы прогноза при хронической сердечной недостаточности. Креативная кардиология. 2007; (): -. DOI:

Ключевые слова: хроническая сердечная недостаточность, ишемическая болезнь сердца, инфаркт миокарда, левый желудочек, фракция выброса, натрийуретические пептиды, предсердный натрийуретический пептид, мозговой натрийуретический пептид

Полнотекстовая версия:  

Аннотация

В большинстве эпидемиологических исследований диагноз хронической сердечной недостаточности (ХСН) выставляется на основании субъективных данных, что не позволяет с высокой достоверностью судить об истинной распространенности данного синдрома. Кроме того, диагностика ХСН на ранних стадиях заболевания сопряжена с определенными трудностями. В настоящее время объективным методом диагностики ХСН может быть определение концентрации натрийуретических пептидов, особенно мозгового натрийуретического пептида (brain natriuretic peptide, BNP), синтезируемого в кардиомиоцитах желудочков. BNP обладает высокими показателями чувствительности, специфичности и положительной прогностической ценности в отношении ХСН; по динамике концентрации данного гормона можно судить об эффективности проводимой терапии и титровать дозу лекарственных препаратов.

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Лео Антонович Бокерия, доктор медицинских наук, профессор, академик РАН и РАМН, директор


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