Современные методы оценки функции тромбоцитов и их клиническое значение у больных с острым коронарным синдромом

Авторы: И. И. Воробьева *

Организация:
Кафедра кардиологии ФПДО Московского государственного медико-стоматологического университета

Для корреспонденции: Сведения доступны для зарегистрированных пользователей.

Тип статьи: Диагностические технологии в кардиологии

Ключевые слова: антиагрегантная терапия, функция тромбоцитов, острый коронарный синдром, агрегометрия, аспирин, клопидогрел

Полнотекстовая версия:  

 

Аннотация

Антиагрегантная терапия является ключевым моментом в лечении острого коронарного синдрома. Несмотря на доказанную клиническую эффективность двойной антиагрегантной терапии аспирином и клопидогрелом, все больший интерес представляет определение индивидуальной чувствительности к антиагрегантам. Резистентность к действию аспирина и клопидогрела ассоциирована с высоким риском развития сердечно-сосудистых событий у больных, страдающих ишемической болезнью сердца. В настоящее время существует большое количество различных лабораторных методов определения функции тромбоцитов и, соответственно, чувствительности к действию антиагрегантных препаратов. В настоящей статье представлены основные методы определения агрегации тромбоцитов с их преимуществами, недостатками и клиническим применением.

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