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  3. Креативная кардиология. 2026; 20(1)
  4. Изучение протеома крови в контексте осложнений острого инфаркта миокарда: достигнутые успехи и дальнейшие перспективы

Изучение протеома крови в контексте осложнений острого инфаркта миокарда: достигнутые успехи и дальнейшие перспективы

Авторы: Кордзая Е.Л., 1 Комиссаров А.А.1, Васильева Е.Ю. 2

Организация:
1 ГБУЗ «Городская клиническая больница им. И.В. Давыдовского Департамента здравоохранения г. Москвы», Москва, Российская Федерация
2 ФГБОУ ВО «Российский университет медицины» Минздрава России, Москва, Российская Федерация

Для корреспонденции: Сведения доступны для зарегистрированных пользователей.

Тип статьи: Обзоры

DOI: https://doi.org/10.24022/1997-3187-2026-20-1-37-45

УДК: 616.127-005.8-06

Для цитирования:  Кордзая Е.Л., Комиссаров А.А., Васильева Е.Ю. Изучение протеома крови в контексте осложнений острого инфаркта миокарда: достигнутые успехи и дальнейшие перспективы. Креативная кардиология. 2026; 20 (1): 37–45. DOI: 10.24022/1997-3187-2026-20-1-37-45

Поступила / Принята к печати:  15.01.2026 / 24.02.2026

Ключевые слова: острый инфаркт миокарда, протеом, биомаркеры

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Аннотация

Развитие жизнеугрожающих осложнений при остром инфаркте миокарда (ОИМ) продолжает оставаться важным фактором, определяющим прогноз у таких пациентов. В связи с этим актуальным представляется поиск биомаркеров, ассоциированных с данными осложнениями. Перспективным инструментом может стать анализ белкового состава (протеома) крови как минимально инвазивный способ получения актуальной информации о происходящих в организме процессах. Настоящий обзор литературы обобщает имеющуюся на сегодняшний день информацию о роли белков плазмы крови в молекулярных механизмах развития осложнений ОИМ, а также оценивается потенциал их использования в качестве прогностических маркеров и возможных терапевтических мишеней. Поиск данных проводился среди источников, опубликованных по указанной тематике в течение последних 20 лет, с использованием электронных ресурсов, таких как PubMed и Google Scholar. Также в обзоре представлены собственные данные.

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Об авторах

  • Кордзая Елена Лериевна, врач-кардиолог; ORCID
  • Комиссаров Алексей Александрович, канд. биол. наук, вед. науч. сотр.; ORCID
  • Васильева Елена Юрьевна, д-р мед. наук, президент1, профессор кафедры кардиологии, заведующая лабораторией атеротромбоза2; ORCID

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Елена Зеликовна Голухова, академик РАН

Елена Зеликовна Голухова, доктор медицинских наук, профессор, академик РАН, директор


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