Investigating blood proteome in relation to complications of acute myocardial infarction: achievements and future prospects

Abstract

The development of life-threatening complications after acute myocardial infarction (AMI) remains a significant factor in determining the prognosis of patients. In this regard, it is important to search for biomarkers that are associated with these complications. One promising approach is to analyze the protein composition of blood (proteome), which can provide valuable information about the ongoing processes in the body in a minimally invasive manner. This literature review aims to summarize the current knowledge about the role of plasma proteins in the molecular mechanisms of AMI complications and their potential use as prognostic markers or therapeutic targets. Data were collected from scientific literature published over the past two decades using electronic resources such as PubMed and Google Scholar. The review also includes original data from the authors.