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Modern concepts in the diagnosis and risk stratification of non-dilated left ventricular cardiomyopathy

Authors: Berdibekov B.Sh., Alexandrova S.A., Bulaeva N.I., Meladze M.G., Golukhova E.Z.

Company: Bakoulev National Medical Research Center for Cardiovascular Surgery, Moscow, Russian Federation

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Type:  Reviews


DOI: https://doi.org/10.24022/1997-3187-2024-18S-S7-S16

For citation: Berdibekov B.Sh., Alexandrova S.A., Bulaeva N.I., Meladze M.G., Golukhova E.Z. Modern concepts in the diagnosis and risk stratification of non-dilated left ventricular cardiomyopathy. Creative Cardiology. 2024; 18 (Special Issue): S7–S16 (in Russ.). DOI: 10.24022/1997-3187-2024-18S-S7-S16

Received / Accepted:  24.09.2024 / 17.10.2024

Keywords: cardiomyopathy, magnetic resonance imaging risk stratification, non-dilated cardiomyopathy

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Abstract

Non-dilated left ventricular cardiomyopathy (NDLVC) is a novel phenotype of cardiomyopathy defined as non–ischemic left ventricular scarring or fatty replacement regardless of the presence of global or regional wall motion abnormalities, or isolated global left ventricular hypokinesia without scarring. This term was officially introduced by the European Society of Cardiology in their 2023 guidelines for managing patients with cardiomyopathies. In recent years, the role of delayed contrast magnetic resonance imaging (MRI) and genetic studies in the diagnosis and risk stratification of cardiomyopathies has significantly increased. This descriptive review discusses the current recommendations for the NDLVC phenotype, with a focus on the capabilities of MRI, genetic testing, and risk stratification for this patient population.

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About Authors

  • Bektur Sh. Berdibekov, Cand. Med. Sci., Senior Researcher, Cardiologist; ORCID
  • Svetlana A. Alexandrova, Cand. Med. Sci., Senior Researcher, Radiologist; ORCID
  • Naida I. Bulaeva, Cand. Biol. Sci., Head of the Department of Coordination and Support of Scientific Research, Cardiologist; ORCID
  • Maya G. Meladze, Researcher, Cardiologist; ORCID
  • Elena Z. Golukhova, Academician of the Russian Academy of Sciences, Dr. Med. Sci., Professor, Director; ORCID

Chief Editor

Elena Z. Golukhova, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, Director of Bakoulev National Medical Research Center for Cardiovascular Surgery


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