Роль полиморфизма гена Р450 в развитии рестенозов коронарных артерий после интервенционных методов лечения у больных ишемической болезнью сердца
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2. Королева, О. С. Генетические аспекты индивидуальной чувствительности к статинам / О. С. Королева, Д. А. Затейщиков, Б. А Сидоренко // Кардиология. — 2005. — Т. 45, № 5. — С. 60-71.
3. Кукес, В. Г. Метаболизм лекарственных средств. Научные основы персонализированной медицины: руководство для врачей / В. Г. Кукес, С. В. Грачев, Д. А Сычев, Г. В. Раменская. — М., 2008. - С. 7-9.
4. Метелица, В. И. Справочник по клинической фармакологии сердечно-сосудистых лекарственных средств. — М.—СПб, 2002. — С. 557-568.
5. Ройтберг, Г. Е. Внутренние болезни. Сердечнососудистая система / Г. Е. Ройтберг, А. В. Струтынский. - М., 2003. - С. 338-344.
6. Соколов, Ю. Н. Инвазивная кардиология и коронарная болезнь / Ю. Н. Соколов, М. Ю. Соколов, Л. Н. Костенко и др. — Киев, 2002. — С. 292-299.
7. Сычев, Д. А. Клиническая фармакогенетика / Д. А. Сычев, Г. В. Раменская, И. В. Игнатьев, B. Г. Кукес. - М., 2007. - С. 93-109.
8. Чрескожные коронарные вмешательства: рекомендации Американской коллегии кардиологов, Американской ассоциации сердца и Общества сердечно-сосудистой ангиографии и интервенций. - 2005. - С. 114-120.
9. Чрескожные коронарные вмешательства: рекомендации Американской коллегии кардиологов, Американской ассоциации сердца и Общества сердечно-сосудистой ангиографии и интервенций. — 2005. — С. 9—17.
10. Badimon, L. Influence of arterial damage and wall shear rate on platelet deposition. Ex vivo study in a swine model / L. Badimon, J. J. Badimon, A. Galvez et al. // Arteriosclerosis. — 1986. — \ b l . 6, № 3. - P. 312-320.
11. Bairn, D. S. Final results of the Balloon vs Optimal Atherectomy Trial (BOAT) / D. S. Bairn, D. E. Cut- Up, S. K. Sharma et al. // Circulation. - 1998. - "Vol. 97, № 4. - P. 322-331.
12. Beyar, R. Frontiers in interventional cardiology / R. Beyar, G. Keren, M. Leon et al. — Berlin: M. Dunitz Ltd, 1998. - P. 460.
13. Bonello, L. Clinical outcomes after implantation of small diameter (=2.5 mm) sirolimus- versus paclitaxel- eluting stents / L. Bonello, A. N. Buch, A. De Labriolle et al. // Int. J. Cardiol. - 2009. - PMID 19201042.
14. Chen, Y. H. Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with angiographic restenosis after coronary stenting / Y. H. Chen, L. Y. Chau, M. W. Lin et al. // Eur. Heart J. - 2004. - Vol. 25, № 1. - P. 39-47.
15. Chiou, K. R. 5A/6A polymorphism of the stromelysin- 1 gene and angiographic restenosis after coronary artery stenting / K. R. Chiou, S. L. Chung, M. J. Charng //J. Chin. Med. Assoc. - 2005. - Vol. 68, № 11.-P. 506-512.
16. Condado, J. A. Long-term angiographic and clinical outcome after percutaneous tra^luminal coronary angioplasty and intracoronary radiation therapy in humans / J. A. Condado, R. ^rtfoksman, O. Gurdiel et al. //Circulation. - 1997. - Vol. 96, № 3. - P. 727-732.
17. De Maat, M. P. Effect of the stromelysin-1 promoter on efficacy of pravastatin in coronary atherosclerosis and restenosis / M. P. de Maat, J. W. Jukema, S. Ye et al. //Am. J. Cardiol. - 1999. - Vol. 83, № 6. - P. 852-856.
18. Edwards, P. A. Sterols and isiprenoids: signaling molecules derived from the biosynthetic pathway / P. A. Edwards, J. Ericsson //Ann. Rev. Biochem. — 1999. - Vol. 68. - P. 157-185.
19. Ferns, G. A. Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF / G. A. Ferns, E. W. Raines, К. H. Sprugel et al. // Science. - 1991. - Vol. 253. - P. 1129-1132.
20. Gruntztg, A. R. Transluminal dilatation of coronary artery stenosis / A. R. Gruntzig // Lancet. - 1978.-Vol. l . - P . 263.
21. Guneri, S. The relationship between angiotensin converting enzyme gene polymorphism, coronary artery disease, and stent restenosis: the role of angiotensin converting enzyme inhibitors in stent restenosis in patients with diabetes mellitus / S. Guneri, N. Baris, D. Aytekin et al. // Int. Heart J. - 2005. Vol. 46, № 5. - P. 889-897.
22. Hanke, H. Time course of smooth muscle cell proliferation in the intima and media of arteries following experimental angioplasty / H. Hanke, Th. Strohschneider, M. Oberhoff et al. // Circ. Research September. - 1990. - Vol. 67, № 3. - P. 651-659.
23. Hermans, W. R. Postangioplasty restenosis rate between segments of the major coronary arteries / W. R. Hermans, B. J. Rensing, J. C. Kelder et al. // Am. J. Cardiol. - 1992. - Vol. 69, № 3. - P. 194-200.
24. Hill, S. A. Reverse cholesterol transport — a review of the process and its clinical implications / S. A. Hill, M. J. McQueen // Clin. Biochem. - 1997. - Vol. 30. - P. 517-525.
25. Holmes, D. R. Restenosis after percutaneous transluminal coronary angioplasty (PTCA): A report from the PTCA Registry of the National Heart, Lung and Blood Institute / D. R. Holmes, R. E. Vliestra, H. C. Smith et al. //Am. J. Cardiol. - 1984. - \ b l . 53. - P. 77C-81C.
26. Hoppmann, P. The 5A/6A polymorphism of the stromelysin-1 gene and restenosis after percutaneous coronary intervention / P. Hoppmann, W. Koch, A. Schomig, A. Kastrati // Eur. Heart J. - 2004. - Vol. 25, № 4. - P. 335-341.
27. Kitahara, H. Angiographic patterns of restenosis after sirolimus-eluting stent implantation / H. Kitahara, Y. Kobayashi, H. Takebayashi et al. // Circ. J. - 2009. - Ш. 73, № 5. - P. 867-871.
28. Koch, W. Angiotensin I-converting enzyme (ACE) inhibitors and restenosis after coronary artery stenting in patients with the DD genotype of the ACE gene / W. Koch, J. Mehffli, N. von Beckerath et al. // J. Am. Coll. Cardiol. - 2003. - \Ы. 41, № 11. - P. 1957-1961.
29. Kolars, J. C. CYP3A4 gene expression in human gut epithelium / J. C. Kolars, K. S. Lown, P. Schniiedlin-Ren et al. // Pharmacogenetics. - 1994. - \Ы. 4. - P. 247-259.
30. Kuntz, R. E. Defining coronary restenosis. Newer clinical and angiographic paradigms / R. E. Kuntz, D. S. Bairn // Circulation. - 1993. - Vol. 88, № 3. - P. 1310-1323.
31. Kurbaan, A. S. Differential restenosis rate of individual coronary artery sites after multivessel angioplasty: implications for revascularization strategy. CABRI Investigators. Coronary Angioplasty versus Bypass Revascularisation Investigation / A. S. Kurbaan, T. J. Bowker, A. F. Rickards // Am. Heart J. - 1998. - Ш. 135, № 4. - P. 703-708.
32. Laskey, W. K. Contemporary trends in coronary intervention: a report from the Registry of the Society for Cardiac Angiography and Interventions / W. K. Laskey, S. Kimmel, R. J. Krone // Catheter Cardiovasc. Interv. - 2000. - Vol. 49, № 1. - P. 19-22.
33. Lemos, P. A. Clinical, angiographic, and procedural predictors of angiographic restenosis after sirolimus-eluting stent implantation in complex patients: an evaluation from the Rapamycin- Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) study / P. A. Lemos, A. Hoye, D. Goedhart et al. // Circulation. - 2004. - Vol. 109, № 11. - P. 1366-1370.
34. Mata, L. A. Clinical and angiographic assessment 6 months after double vessel percutaneous coronary angioplasty / L. A. Mata, X. Bosch, P. R. David et al. // JACC. - 1985. - Vol. 6. - P. 1239-1244.
35. Mintz, G. S. Intravascular ultrasound evaluation of the effect of rotational atherectomy in obstructive atherosclerotic coronary artery disease / G. S. Mintz, B. N. Pofkin, G. Keren et al. // Circulation. - 1992. - "Vol. 86, № 5. - P. 1383-1393.
36. Peters, B. J. Effectiveness of statins in the reduction of the risk of myocardial infarction is modified by the GNB3 C825T variant / B. J. Peters, A. H. Maitland- van der Zee, В. H. Strieker et al. // Pharmacogenet. Genomics. - 2008. - Vol. 18, № 7. - P. 631-636.
37. Puccetti, L. Genetic influence in antithrombotic actions of atorvastatin in hypercholesterolaemia / L. Puccetti, F. Brani, A. L. Pasqui et al. // Eur. J. Clin. Invest. - 2008. - Vol. 38, № 1. - P. 11-16.
38. Ribichini, F. Association study of the I /D polymorphism and plasma angiotensin-converting enzyme (ACE) as risk factors for stent restenosis / F. Ribichini, V. Ferrero, G. Matullo et al. // Clin. Sci. (Lond). - 2004. - Vol. 107, № 4. - P. 381-389.
39. Schmitz, H. J. Greater initial dilatation gives better late angiographic results in percutaneous coronary angioplasty (PTCA) (abstr.) / H. J. Schmitz, T. Kiesslich, S. Effert // Circulation. - 1982. - Vol. 66. - P. 11-23 (Suppl. 11).
40. Schwartz, R- The restenosis paradigm revisited: an alternative proposal for cellular mechanisms / R. Schwartz, D. Holmes, E. Topol // JACC. - 1992. - Vol. 20, № 5. - P. 1284-1293.
41. Serruys, P. W. A comparison of balloon-expandable- stent implantation with balloon angioplasty in patients with coronary artery disease. Benestent Study Group / P. W. Serruys, P. de Jaegere, F. Kiemeneij et al. // N. Engl. J. Med. - 1994. - Vol. 331, № 8. - P. 489-495.
42. Serruys, P. W. A randomized placebo-controlled trial of fluvastatin for prevention of restenosis after successful coronary balloon angioplasty; final results of the fluvastatin angiographic restenosis (FLARE) trial / P. W. Serruys, D. P. Foley, G. Jackson et al. // Eur. Heart J. - 1999. - Ш. 20, № 1. - P. 58-69.
43. Serruys, P. W. Incidence of restenosis after successful coronary angioplasty: a time-related phenomenon. A quantitative angiographic study in 342 consecutive patients at 1, 2, 3, and 4 months / P. W. Serruys, H. E. Luijten, K. J. Beatt et al. // Circulation. - 1988. - Ш. 77, № 2. - P. 361-371.
44. Tang, В. K. Variable activation of lovastatin by hydrolytic enzymes in human plasma and Uver / В. K. Tang, W. Kalow // Eur. J. Clin. Pharmacol. - 1995. - Vol. 47. - P. 449-451.
45. Walter, D. H. Effect of statin therapy on restenosis after coronary stent implantation / D. H. Walter, V. Schachinger, M. Eisner et al. // Am. J. Cardiol. - 2000. - Vol. 85, № 8. - P. 962-968.
46. Wilkinson, G. R Pharmacokinetics: the dynamics of drug absorbtion, distribution and eUmination / G. R Wilkinson // Goodman & Gilman's the pharmacological basis of therapeutics; eds J. G. Hardman, L. E. Limbird, A. G. Gilman. - 10th ed. - New York, 2008.
47. Zhang, F. L. Protein prenylation: molecular mechanisms and functional consequences / F. L. Zhang, P. J. Casey //Ann. Rev. Biochem. - 1996. - \ 65. - P. 241-269.
Abstract
Coronary artery restenosis after interventional treatment is one of the most significant problem. Drug therapy after coronary stent implantation is going to prevent such life-threatening complication as stent restenosis. A number of studies shows that statins may prevent restenosis, according to other investigations, they does not influence on frequency of restenosis. Actual direction of researches is searching the relations between gene polymorphism taking part in metabolism of statins and restenosis of coronary arteries after interventional treatment.References
1. Бабунашвили, А. М. Эндопротезирование (стентирование) венечных артерий сердца / A. М. Бабунашвили. - М., 2001. - С. 34-45.2. Королева, О. С. Генетические аспекты индивидуальной чувствительности к статинам / О. С. Королева, Д. А. Затейщиков, Б. А Сидоренко // Кардиология. — 2005. — Т. 45, № 5. — С. 60-71.
3. Кукес, В. Г. Метаболизм лекарственных средств. Научные основы персонализированной медицины: руководство для врачей / В. Г. Кукес, С. В. Грачев, Д. А Сычев, Г. В. Раменская. — М., 2008. - С. 7-9.
4. Метелица, В. И. Справочник по клинической фармакологии сердечно-сосудистых лекарственных средств. — М.—СПб, 2002. — С. 557-568.
5. Ройтберг, Г. Е. Внутренние болезни. Сердечнососудистая система / Г. Е. Ройтберг, А. В. Струтынский. - М., 2003. - С. 338-344.
6. Соколов, Ю. Н. Инвазивная кардиология и коронарная болезнь / Ю. Н. Соколов, М. Ю. Соколов, Л. Н. Костенко и др. — Киев, 2002. — С. 292-299.
7. Сычев, Д. А. Клиническая фармакогенетика / Д. А. Сычев, Г. В. Раменская, И. В. Игнатьев, B. Г. Кукес. - М., 2007. - С. 93-109.
8. Чрескожные коронарные вмешательства: рекомендации Американской коллегии кардиологов, Американской ассоциации сердца и Общества сердечно-сосудистой ангиографии и интервенций. - 2005. - С. 114-120.
9. Чрескожные коронарные вмешательства: рекомендации Американской коллегии кардиологов, Американской ассоциации сердца и Общества сердечно-сосудистой ангиографии и интервенций. — 2005. — С. 9—17.
10. Badimon, L. Influence of arterial damage and wall shear rate on platelet deposition. Ex vivo study in a swine model / L. Badimon, J. J. Badimon, A. Galvez et al. // Arteriosclerosis. — 1986. — \ b l . 6, № 3. - P. 312-320.
11. Bairn, D. S. Final results of the Balloon vs Optimal Atherectomy Trial (BOAT) / D. S. Bairn, D. E. Cut- Up, S. K. Sharma et al. // Circulation. - 1998. - "Vol. 97, № 4. - P. 322-331.
12. Beyar, R. Frontiers in interventional cardiology / R. Beyar, G. Keren, M. Leon et al. — Berlin: M. Dunitz Ltd, 1998. - P. 460.
13. Bonello, L. Clinical outcomes after implantation of small diameter (=2.5 mm) sirolimus- versus paclitaxel- eluting stents / L. Bonello, A. N. Buch, A. De Labriolle et al. // Int. J. Cardiol. - 2009. - PMID 19201042.
14. Chen, Y. H. Heme oxygenase-1 gene promoter microsatellite polymorphism is associated with angiographic restenosis after coronary stenting / Y. H. Chen, L. Y. Chau, M. W. Lin et al. // Eur. Heart J. - 2004. - Vol. 25, № 1. - P. 39-47.
15. Chiou, K. R. 5A/6A polymorphism of the stromelysin- 1 gene and angiographic restenosis after coronary artery stenting / K. R. Chiou, S. L. Chung, M. J. Charng //J. Chin. Med. Assoc. - 2005. - Vol. 68, № 11.-P. 506-512.
16. Condado, J. A. Long-term angiographic and clinical outcome after percutaneous tra^luminal coronary angioplasty and intracoronary radiation therapy in humans / J. A. Condado, R. ^rtfoksman, O. Gurdiel et al. //Circulation. - 1997. - Vol. 96, № 3. - P. 727-732.
17. De Maat, M. P. Effect of the stromelysin-1 promoter on efficacy of pravastatin in coronary atherosclerosis and restenosis / M. P. de Maat, J. W. Jukema, S. Ye et al. //Am. J. Cardiol. - 1999. - Vol. 83, № 6. - P. 852-856.
18. Edwards, P. A. Sterols and isiprenoids: signaling molecules derived from the biosynthetic pathway / P. A. Edwards, J. Ericsson //Ann. Rev. Biochem. — 1999. - Vol. 68. - P. 157-185.
19. Ferns, G. A. Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF / G. A. Ferns, E. W. Raines, К. H. Sprugel et al. // Science. - 1991. - Vol. 253. - P. 1129-1132.
20. Gruntztg, A. R. Transluminal dilatation of coronary artery stenosis / A. R. Gruntzig // Lancet. - 1978.-Vol. l . - P . 263.
21. Guneri, S. The relationship between angiotensin converting enzyme gene polymorphism, coronary artery disease, and stent restenosis: the role of angiotensin converting enzyme inhibitors in stent restenosis in patients with diabetes mellitus / S. Guneri, N. Baris, D. Aytekin et al. // Int. Heart J. - 2005. Vol. 46, № 5. - P. 889-897.
22. Hanke, H. Time course of smooth muscle cell proliferation in the intima and media of arteries following experimental angioplasty / H. Hanke, Th. Strohschneider, M. Oberhoff et al. // Circ. Research September. - 1990. - Vol. 67, № 3. - P. 651-659.
23. Hermans, W. R. Postangioplasty restenosis rate between segments of the major coronary arteries / W. R. Hermans, B. J. Rensing, J. C. Kelder et al. // Am. J. Cardiol. - 1992. - Vol. 69, № 3. - P. 194-200.
24. Hill, S. A. Reverse cholesterol transport — a review of the process and its clinical implications / S. A. Hill, M. J. McQueen // Clin. Biochem. - 1997. - Vol. 30. - P. 517-525.
25. Holmes, D. R. Restenosis after percutaneous transluminal coronary angioplasty (PTCA): A report from the PTCA Registry of the National Heart, Lung and Blood Institute / D. R. Holmes, R. E. Vliestra, H. C. Smith et al. //Am. J. Cardiol. - 1984. - \ b l . 53. - P. 77C-81C.
26. Hoppmann, P. The 5A/6A polymorphism of the stromelysin-1 gene and restenosis after percutaneous coronary intervention / P. Hoppmann, W. Koch, A. Schomig, A. Kastrati // Eur. Heart J. - 2004. - Vol. 25, № 4. - P. 335-341.
27. Kitahara, H. Angiographic patterns of restenosis after sirolimus-eluting stent implantation / H. Kitahara, Y. Kobayashi, H. Takebayashi et al. // Circ. J. - 2009. - Ш. 73, № 5. - P. 867-871.
28. Koch, W. Angiotensin I-converting enzyme (ACE) inhibitors and restenosis after coronary artery stenting in patients with the DD genotype of the ACE gene / W. Koch, J. Mehffli, N. von Beckerath et al. // J. Am. Coll. Cardiol. - 2003. - \Ы. 41, № 11. - P. 1957-1961.
29. Kolars, J. C. CYP3A4 gene expression in human gut epithelium / J. C. Kolars, K. S. Lown, P. Schniiedlin-Ren et al. // Pharmacogenetics. - 1994. - \Ы. 4. - P. 247-259.
30. Kuntz, R. E. Defining coronary restenosis. Newer clinical and angiographic paradigms / R. E. Kuntz, D. S. Bairn // Circulation. - 1993. - Vol. 88, № 3. - P. 1310-1323.
31. Kurbaan, A. S. Differential restenosis rate of individual coronary artery sites after multivessel angioplasty: implications for revascularization strategy. CABRI Investigators. Coronary Angioplasty versus Bypass Revascularisation Investigation / A. S. Kurbaan, T. J. Bowker, A. F. Rickards // Am. Heart J. - 1998. - Ш. 135, № 4. - P. 703-708.
32. Laskey, W. K. Contemporary trends in coronary intervention: a report from the Registry of the Society for Cardiac Angiography and Interventions / W. K. Laskey, S. Kimmel, R. J. Krone // Catheter Cardiovasc. Interv. - 2000. - Vol. 49, № 1. - P. 19-22.
33. Lemos, P. A. Clinical, angiographic, and procedural predictors of angiographic restenosis after sirolimus-eluting stent implantation in complex patients: an evaluation from the Rapamycin- Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) study / P. A. Lemos, A. Hoye, D. Goedhart et al. // Circulation. - 2004. - Vol. 109, № 11. - P. 1366-1370.
34. Mata, L. A. Clinical and angiographic assessment 6 months after double vessel percutaneous coronary angioplasty / L. A. Mata, X. Bosch, P. R. David et al. // JACC. - 1985. - Vol. 6. - P. 1239-1244.
35. Mintz, G. S. Intravascular ultrasound evaluation of the effect of rotational atherectomy in obstructive atherosclerotic coronary artery disease / G. S. Mintz, B. N. Pofkin, G. Keren et al. // Circulation. - 1992. - "Vol. 86, № 5. - P. 1383-1393.
36. Peters, B. J. Effectiveness of statins in the reduction of the risk of myocardial infarction is modified by the GNB3 C825T variant / B. J. Peters, A. H. Maitland- van der Zee, В. H. Strieker et al. // Pharmacogenet. Genomics. - 2008. - Vol. 18, № 7. - P. 631-636.
37. Puccetti, L. Genetic influence in antithrombotic actions of atorvastatin in hypercholesterolaemia / L. Puccetti, F. Brani, A. L. Pasqui et al. // Eur. J. Clin. Invest. - 2008. - Vol. 38, № 1. - P. 11-16.
38. Ribichini, F. Association study of the I /D polymorphism and plasma angiotensin-converting enzyme (ACE) as risk factors for stent restenosis / F. Ribichini, V. Ferrero, G. Matullo et al. // Clin. Sci. (Lond). - 2004. - Vol. 107, № 4. - P. 381-389.
39. Schmitz, H. J. Greater initial dilatation gives better late angiographic results in percutaneous coronary angioplasty (PTCA) (abstr.) / H. J. Schmitz, T. Kiesslich, S. Effert // Circulation. - 1982. - Vol. 66. - P. 11-23 (Suppl. 11).
40. Schwartz, R- The restenosis paradigm revisited: an alternative proposal for cellular mechanisms / R. Schwartz, D. Holmes, E. Topol // JACC. - 1992. - Vol. 20, № 5. - P. 1284-1293.
41. Serruys, P. W. A comparison of balloon-expandable- stent implantation with balloon angioplasty in patients with coronary artery disease. Benestent Study Group / P. W. Serruys, P. de Jaegere, F. Kiemeneij et al. // N. Engl. J. Med. - 1994. - Vol. 331, № 8. - P. 489-495.
42. Serruys, P. W. A randomized placebo-controlled trial of fluvastatin for prevention of restenosis after successful coronary balloon angioplasty; final results of the fluvastatin angiographic restenosis (FLARE) trial / P. W. Serruys, D. P. Foley, G. Jackson et al. // Eur. Heart J. - 1999. - Ш. 20, № 1. - P. 58-69.
43. Serruys, P. W. Incidence of restenosis after successful coronary angioplasty: a time-related phenomenon. A quantitative angiographic study in 342 consecutive patients at 1, 2, 3, and 4 months / P. W. Serruys, H. E. Luijten, K. J. Beatt et al. // Circulation. - 1988. - Ш. 77, № 2. - P. 361-371.
44. Tang, В. K. Variable activation of lovastatin by hydrolytic enzymes in human plasma and Uver / В. K. Tang, W. Kalow // Eur. J. Clin. Pharmacol. - 1995. - Vol. 47. - P. 449-451.
45. Walter, D. H. Effect of statin therapy on restenosis after coronary stent implantation / D. H. Walter, V. Schachinger, M. Eisner et al. // Am. J. Cardiol. - 2000. - Vol. 85, № 8. - P. 962-968.
46. Wilkinson, G. R Pharmacokinetics: the dynamics of drug absorbtion, distribution and eUmination / G. R Wilkinson // Goodman & Gilman's the pharmacological basis of therapeutics; eds J. G. Hardman, L. E. Limbird, A. G. Gilman. - 10th ed. - New York, 2008.
47. Zhang, F. L. Protein prenylation: molecular mechanisms and functional consequences / F. L. Zhang, P. J. Casey //Ann. Rev. Biochem. - 1996. - \ 65. - P. 241-269.
