Амилоидоз сердца: клинический случай и литературная справка

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Abstract

Amyloidosis and management of patients suffering of this disease is quite a task. Amyloidosis cannot be designated as a rare disease particularly in consideration of the forms, number of which increases with age. Thus over 3000 cases of amyloidosis were annually registered in the USA. Amyloidosis which can be both hereditary and acquired disease is a systemic disease whereby one or more organs are involved. This paper deals with peculiarities of heart amyloidosis clinical manifestations, its diagnosis using contemporary laboratory instrumental techniques. Heart amyloidosis manifests by amyloid accumulation around collagen in the stroma of the organ which results in myocardial thickening and induration and due to this in acute reduction of its compliance and development of restrictive cardiomyopathy. Timely diagnosis based on contemporary biochemical, morphological and clinical studies which eventually can improve prognosis for a disease is essential.

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Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery