Abstract
The results of numerous studies of last decades have confirmed the key role of endothelium in regulation of vascular homeostasis.
The normal endothelial function involves the balance of processes such as vasoconstriction and vasodilation, production of factors
of inflammation and vessel proliferation, participation in blood clotting and vessel remodeling. It is known that with increasing
oxidative stress and accumulation of free radical combinations the endothelial function can impair, atherosclerosis progress as well
as other cardiovascular complications [1, 2, 3, 4]. The purpose of this review has been to summarize and analyse a number of works
relating to endothelial dysfunction, oxidative stress and their obvious role in development of cardiovascular pathology [5]
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