Coronary artery stenting in patients with coronary heart diseaseand cancer

Authors: Nikitina T.G.1, Dombrovskiy M.M.1, Alekyan B.G.2, Davydov M.I..3, Bockeria L.A.1

Company: 1 A.N. Bakoulev Scientific Center for Cardiovascular Surgery of Ministry of Health of the Russian Federation; Rublevskoe shosse, 135, Moscow, 121552, Russian Federation;
2 A.V. Vishnevsky Institute of Surgery of Ministry of Health of the Russian Federation; Bol'shaya Serpukhovskaya ulitsa, 27, Moscow, 115478, Russian Federation;
3 N.N. Blokhin Russian Oncological Scientific Center of Ministry of Health of the Russian Federation; Kashirskoe shosse, 23, Moscow, 115478, Russian Federation

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DOI: https://doi.org/10.15275/kreatkard.2016.04.04

For citation: Nikitina T.G., Dombrovskiy M.M., Alekyan B.G., Davydov M.I., Bockeria L.A. Coronary artery stenting in patients with coronary heart diseaseand cancer. Creative Cardiology. 2016; 10 (4): 296-305.(in Russ.).

Keywords: percutaneous coronary intervention oncopathology coronary heart disease staged treatment

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Abstract

Objective. Analysis of the immediate and long-term results of percutaneous coronary intervention in patients with coronary heart disease (CHD) and oncopathology.
Material and methods. This paper presents the results of a two-stage treatment of 41 patients (35 men and 6 women) with CHD and oncopathology. The mean age was 67.6±6.4 years. The first step was performed percutaneous coronary intervention (PCI), and the second – the treatment of cancer pathology (20 patients underwent surgical treatment, 18 – chemotherapy or radiation therapy, and 3 – combined treatment).
Results. There were no cases of intraoperative and hospital mortality during the two-stage treatment of coronary heart disease and cancer pathology. Over the entire period of observation a death due to acute coronary syndrome was not registered. One case of Q-wave myocardial infarction was registered in a patient in 3 years after myocardial revascularization (she died in 4 months after myocardial infarction due to progression of cancer). The mortality rate for five years of follow-up was 22%: 5 (12.2%) patients died from cancer pathology at the first year after PCI, 4 (9.8%) patients died of cancer pathology in 1.5, 2, 3.5 and 4.5 years after percutaneous revascularization. The majority (96.9%) of patients had received good indicators of quality of life in the long term period of observation.
Conclusion. Percutaneous coronary intervention - an effective and safe method for myocardial revascularization in patients with coronary artery disease and oncopathology. The use of endovascular myocardial revascularization in the first stage of cancer patients reduces the risk of cardiovascular complications during the treatment of cancer (surgery, chemotherapy, radiation therapy).

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Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery