Dual-energy computed tomography coronary angiography in patients with chronic ischemic heart disease

Authors: Boldyreva K.M., Aslanidis I.P., Dorofeev A.V., Rychina I.E., Dariy O.Yu., Golukhova E.Z.

Company: Bakoulev National Medical Research Center for Cardiovascular Surgery, Moscow, Russian Federation

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Type:  Clinical Cases

DOI: https://doi.org/10.24022/1997-3187-2022-16-3-413-420

For citation: Boldyreva K.M., Aslanidi I.P., Dorofeev A.V., Rychina I.E., Dariy O.Yu., Golukhova E.Z. Dual-energy computed tomography coronary angiography in patients with chronic ischemic heart disease. Creative Cardiology. 2022; 16 (3): 413–20 (in Russ.). DOI: 10.24022/1997-3187-2022-16-3-413-420

Received / Accepted:  05.07.2022 / 26.08.2022

Keywords: dual-energy computed tomography CT perfusion myocardial infarction coronary heart disease iodine cards

Full text:  



Description of opportunity of computed tomography (CT) coronary angiography with static dual-energy CT perfusion in rest status of myocardium for assessment of coronary arteries and postischemic (scars) changes in patients with coronary arteries disease. The aim of our study was to show the assessment patency of revascularization segments of coronary arteries and dynamic observation in 2 clinical cases of men ages up to 60 years old who had a history of myocardial infarction and symptoms of chronic coronary arteries disease. Both patients underwent myocardium revascularization after acute myocardial infarction (Q-myocardial infarction). CT examinations were performed using dual-tube CT Siemens SOMATOM Force in double energy scan mode with results postprocessing on Syngo.via workstation. Оmnipaque 350 was used for contrast enhancement. The violation of perfusion in modelling myocardium iodine maps in peak of passage of contrast agent was detected. The area of hypoperfusion corresponded area of damage arteries. Indications of iodine concentration in area of hypoperfusion was 0,0–0,1 mg/ml for patient А, and 3,2 mg/ml for non-damaged arteria area, while for patient B, the concentration of iodine in hypoperfusion was 0,5–0,6 mg/ml and 4,2 mg/ml for non-damaged arteria area. Dualenergy myocardial CT perfusion in combination with the standard CT coronary angiography protocol in patients with chronic CAD is a promising method capable of detecting the presence of perfusion defects in the myocardium, which reliably indicates myocardial fibrous replacement.


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About Authors

  • Kiriena M. Boldyreva, Postgraduate, Junior Researcher; ORCID
  • Irakliy P. Aslanidis, Dr. Med. Sci., Professor, Head of Department, Deputy Director; ORCID
  • Aleksey V. Dorofeev, Cand. Med. Sci., Head of Department; ORCID
  • Inna E. Rychina, Cand. Med. Sci., Senior Research Associate, Head of Department; ORCID
  • Ol’ga Yu. Dariy, Cand. Med. Sci., Radiologist, ORCID
  • Elena Z. Golukhova, Dr. Med. Sci., Professor, Academician of Russian Academy of Sciences, Head of Department, Director; ORCID

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery