Measurement of maximal oxygen uptake: physiological basis and clinical applications

Authors: N.N. Koloskova, K.V. Shatalov, L.A. Bockeria

Company: A.N. Bakoulev Scientific Center for Cardiovascular Surgery of Russian Academy of Medical Sciences; Rublevskoe shosse, 135, Moscow, 121552, Russian Federation


For citation: Koloskova N.N., Shatalov K.V., Bockeria L.A. Measurement of maximal oxygen uptake: physiological basis and clinical applications. Creative Cardiology. 2014; 1: 48-57

Keywords: Antoine Laurent Lavoisier cardiopulmonary exercise testing peak VO2 chronic heart failure.

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Abstract

Cardiopulmonary exercise testing (CPET), based upon the high-density profiles of the ventilatory and pulmonary gas exchange responses, is a relatively new medical technology used to clinically practice in 1975. However, this history starts with Antoine Laurent Lavoisier who was the first person to measure oxygen uptake during exercise. Now cardiopulmonary exercise testing with ventilatory expired gas analysis has proven to be a valuable tool for assessing patients with chronic heart failure (CHF). The maximal oxygen uptake (peak VO2) is used in risk stratification of patients with CHF.

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Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery