Takotsubo cardiomyopathy (part 3)

Authors: A.M. Lebedeva, E.Yu. Vasil’eva, A.V. Shpektor

Company: Cardiology Chair for Post-Diploma Education Faculty of A.I. Evdokimov Moscow State Medical-Stomatological University of Ministry of Health of the Russian Federation.


For citation: Lebedeva A.M., Vasil’eva E.Yu., Shpektor A.V. Takotsubo cardiomyopathy (part 3). Kreativnaya kardiologiya. 2013; 1: 82-87 (in Russian)

Keywords: takotsubo cardiomyopathy acute myocardial infarction with ST-segment elevation myocardial enzymes troponin left ventricular apical ballooning beta blockers

Download
Full text:  

 

Abstract

Takotsubo cardiomyopathy (ТСМ) is a rare type of cardiomyopathy characterized by transient myocardial contractile dysfunction. In the previous lectures we considered the epidemiology as well as well-recognized suggestion of the cardiomyopathy pathogenesis. The final lecture described the basic clinical manifestations of takotsubo cardiomyopathy, including variants of localization of myocardial contractile dysfunction in acute phase of takotsubo cardiomyopathy. The most frequent complications of the syndrome have been considered separately. In conclusion the main principles of treatment of takotsubo cardiomyopathy have been noted.

References

1. Bybee K.A., Kara T., Prasad A. et al. Systematic review: transient left ventricular apical ballooning: a syndrome that mimics ST-segment elevation myocardial infarction. Ann. Intern. Med. 2004; 141 (11): 858–65. 2. Kawai S., Kitabatake A., Tomoike H. Guidelines for diagnosis of takotsubo (ampulla) cardiomyopathy. Circ. J. 2007; 71 (6): 990–2. 3. Бокерия Л.А., Бокерия О.Л., Густова И.А. Синдром шаровидной деформации верхушки левого желудочка. Современное состояние проблемы. Бюллетень НЦССХ им. А.Н. Бакулева РАМН. 2007; 8 (6): 61–70. 4. Hertting K., Krause K., Harle T. et al. Transient left ventricular apical ballooning in a community hospital in Germany. Int. J. Cardiol. 2006; 112 (3): 282–8. 5. Gianni M., Dentali F., Grandi A.M. et al. Apical ballooning syndrome or takotsubo cardiomyopathy: a systematic review. Eur. Heart J. 2006; 27 (13): 1523–9. 6. Akashi Y.J., Nef H.M., Mollmann H. et al. Stress cardiomyopathy. Annu. Rev. Med. 2010; 61: 271–86. 7. Nef H.M., Mollmann H., Hilpert P. et al. Activated cell survival cascade protects cardiomyocytes from cell death in Tako-Tsubo cardiomyopathy. Eur. J. Heart Fail. 2009; 11 (8): 758–64. 8. Nef H.M., Mollmann H., Kostin S. et al. Tako-Tsubo cardiomyopathy: intraindividual structural analysis in the acute phase and after functional recovery. Eur. Heart J. 2007; 28 (20): 2456–64. 9. Nef H.M., Mollmann H., Troidl C. et al. Abnormalities in intracellular Ca2+ regulation contribute to the pathomechanism of Tako- Tsubo cardiomyopathy. Eur. Heart J. 2009; 30 (17): 2155–64. 10. Wittstein I.S., Thiemann D.R., Lima J.A. et al. Neurohumoral features of myocardial stunning due to sudden emotional stress. N. Engl. J. Med. 2005; 352 (6): 539–48. 11. Sharkey S.W. Electrocardiogram mimics of acute ST-segment elevation myocardial infarction: insights from cardiac magnetic resonance imaging in patients with tako-tsubo (stress) cardiomyopathy. J. Electrocardiol. 2008; 41 (6): 621–5. 12. Akashi Y.J., Nakazawa K., Sakakibara M. et al. The clinical features of takotsubo cardiomyopathy. QJM. 2003; 96 (8): 563–73. 13. Tsuchihashi K., Ueshima K., Uchida T. et al. Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction. Angina Pectoris-Myocardial Infarction Investigations in Japan. J. Am. Coll. Cardiol. 2001; 38 (1): 11–8. 14. Bahit M.C., Criger D.A., Ohman E.M. et al. Thresholds for the electrocardiographic change range of biochemical markers of acute myocardial infarction (GUSTO-IIa data). Am. J. Cardiol. 2002; 90 (3): 233–7. 15. Ito K., Sugihara H., Kinoshita N. et al. Assessment of Takotsubo cardiomyopathy (transient left ventricular apical ballooning) using 99mTc-tetrofosmin, 123I-BMIPP, 123I-MIBG and 99mTc-PYP myocardial SPECT. Ann. Nucl. Med. 2005; 19 (6): 435–45. 16. Donohue D., Movahed M.R. Clinical characteristics, demographics and prognosis of transient left ventricular apical ballooning syndrome. Heart Fail. Rev. 2005; 10 (4): 311–6. 17. Sharkey S.W., Lesser J.R., Zenovich A.G. et al. Acute and reversible cardiomyopathy provoked by stress in women from the United States. Circulation. 2005; 111 (4): 472–9. 18. Fazio G., Novo G., Azzarelli S. et al. Transient mid-ventricular dyskinesia: a variant of Takotsubo syndrome. Int. J. Cardiol. 2008; 129 (2): 272–3. 19. Krishnan U., Zacharzewski A., Schmitt M. Nonapical tako-tsubo cardiomyopathy associated with coronary slow flow: a case report and review of the literature. Clin. Cardiol. 2009; 32 (11): E63–6. 20. Proietti R., Rognoni A., Ardizzone F. et al. Atypical Takotsubo syndrome during anagrelide therapy. J. Cardiovasc. Med. (Hagerstown). 2009; 10 (7): 546–9. 21. Bonnemeier H., Ortak J., Burgdorf C. et al. «The artichoke heart»: the inverse counterpart of left ventricular apical ballooning. Resuscitation. 2007; 72 (3): 342–3. 22. Strunk B., Shaw R.E., Bull S. et al. High incidence of focal left ventricular wall motion abnormalities and normal coronary arteries in patients with myocardial infarctions presenting to a community hospital. J. Invasive Cardiol. 2006; 18 (8): 376–81. 23. Elesber A.A., Prasad A., Bybee K.A. et al. Transient cardiac apical ballooning syndrome: prevalence and clinical implications of right ventricular involvement. J. Am. Coll. Cardiol. 2006; 47 (5): 1082–3. 24. Haghi D., Athanasiadis A., Papavassiliu T. et al. Right ventricular involvement in Takotsubo cardiomyopathy. Eur. Heart J. 2006; 27 (20): 2433–9. 25. Arbel Y., Dvir D., Feinberg M.S. et al. The association between right coronary artery morphology and endothelial function. Int. J. Cardiol. 2007; 115 (1): 19–23. 26. Akashi Y.J., Nakazawa K., Sakakibara M. et al. 123I-MIBG myocardial scintigraphy in patients with «takotsubo» cardiomyopathy. J. Nucl. Med. 2004; 45 (7): 1121–7. 27. Kawano H., Okada R., Yano K. Histological study on the distribution of autonomic nerves in the human heart. Heart Vessels. 2003; 18 (1): 32–9. 28. Akashi Y.J., Tejima T., Sakurada H. et al. Left ventricular rupture associated with Takotsubo cardiomyopathy. Mayo Clin. Proc. 2004; 79 (6): 821–4. 29. Haghi D., Rohm S., Suselbeck T. et al. Incidence and clinical significance of mitral regurgitation in Takotsubo cardiomyopathy. Clin. Res. Cardiol. 2009; 99 (2): 93–8. 30. Jaguszewski M., Fijalkowski M., Nowak R. et al. Ventricular rupture in Takotsubo cardiomyopathy. Eur. Heart J. 2012; 33: 1027. 31. Yoshioka T., Hashimoto A., Tsuchihashi K. et al. Clinical implications of midventricular obstruction and intravenous propranolol use in transient left ventricular apical ballooning (Tako-tsubo cardiomyopathy). Am. Heart J. 2008; 155 (3): 526 e521–7. 32. Prasad A. Apical ballooning syndrome: an important differential diagnosis of acute myocardial infarction. Circulation. 2007; 115 (5): 56–9. 33. Palla A.R., Dande A.S., Petrini J. et al. Pretreatment with low-dose beta-adrenergic antagonist therapy does not affect severity of Takotsubo cardiomyopathy. Clin. Cardiol. 2012; 35: 478–81.

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery