Clinical characteristics associated with moderate and severe sleep-disordered breathing syndrome in patients with ischemic stroke HTML

Authors: A.V. Fonyakin, L.A. Geraskina, M.Yu. Maksimova, G.M. Lutokhin

Company: Researh Center of Neurology, Volokolamskoe shosse, 80, Moscow, 125367, Russian Federation

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Heading: Original articles

UDC: 616.831-005.4:616.24-008.4
DOI: https://doi.org/10.24022/1997-3187-2018-12-3-225-235

For citation: Fonyakin A.V., Geraskina L.A., Maksimova M.Yu., Lutokhin G.M. Clinical characteristics associated with moderate and severe sleep-disordered breathing syndrome in patients with ischemic stroke. Creative Cardiology. 2018; 12 (3): 225–35 (in Russ.). DOI: 10.24022/1997-3187-2018-12-3-225-235

Received / Accepted:  16.03.2018/04.04.2018

Key Words: ischemic stroke sleep-disordered breathing syndrome

Abstract

Objective. To determine the clinical signs associated with the moderate and severe sleep-disordered breathing syndrome (SDBS) in patients in the acute period of ischemic stroke.

Material and methods. 78 patients with ischemic stroke were examined. The presence and structure of SDBS was studied by cardiorespiratory monitoring on the 2–5th day from the onset of stroke.

Results. SDBS was detected in 69 (88%) patients, mainly obstructive. The apnea/hypopnea index averaged 17 [9; 25]. 46 (59.0%) patients had moderate and severe SDBS. As a result of mathematical processing, a model was obtained from 8 features associated with the presence of moderate and severe SDBS, which included: age 68 years and older, males, an estimated modified Rankin score of 3 or more, cardioembolic stroke, stenosis of the brachiocephalic arteries more than 70%, congestive heart failure, recurrent stroke, the involvement of an insula in the cerebral infarction.

Conclusions. When identifying these clinical signs in patients with ischemic stroke cardiorespiratory monitoring
should be recommended. Patients with moderate/severe SDBS need timely correction of respiratory disorders in
order to improve early neurologic recovery and long-term cardiovascular prognosis.

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About Authors

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, Director of Bakoulev National Medical Research Center for Cardiovascular Surgery