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Genetic predictors of complications after coronary artery bypass grafting

Authors: Abramovskikh O.S., Belov D.V., Zotova M.A., Fokin A.A., Lukin O.P.

Company: 1 South Ural State Medical University; Chelyabinsk, Russian Federation
2 Federal Center for Cardiovascular Surgery, Chelyabinsk; Chelyabinsk, Russian Federation

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Type:  Reviews


DOI: https://doi.org/10.24022/1997-3187-2023-17-1-11-24

For citation: Abramovskikh O.S., Belov D.V., Zotova M.A., Fokin A.A., Lukin O.P. Genetic predictors of complications after coronary artery bypass grafting. Creative Cardiology. 2023; 17 (1): 11–24 (in Russ.). DOI: 10.24022/1997-3187-2023-17-1-11-24

Received / Accepted:  22.04.2022 / 06.03.2023

Keywords: cardiac surgery complications genetic predictors cardiopulmonary bypass



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Abstract

Despite the improvement of surgical techniques, anesthetic management and perioperative management of patients, the problem of the development of complications after cardiac surgery remains relevant. The purpose of our study: to present literature data on the role of genetic predictors of postoperative complications (myocardial infarction and postoperative bleeding). Genetic predictors can be used as tools for predicting the risks of postoperative complications in operated patients under cardiopulmonary bypass. In the future, the development of predictive models based on preoperative genetic analysis will help reduce in-hospital cardiovascular mortality.

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About Authors

  • Olga S. Abramovskikh, Dr. Med. Sci., Associate Professor, Chief of Chair; ORCID
  • Dmitriy V. Belov, Cand. Med. Sci., Associate Professor of the Department of Hospital Surgery of SUSMU, Cardiovascular Surgeon of FCCS; ORCID
  • Mariya A. Zotova, Cand. Biol. Sci., Senior Researcher; ORCID
  • Aleksey A. Fokin, Dr. Med. Sci., Professor, Chief of Chair;
  • Oleg P. Lukin, Dr. Med. Sci., Chief Physician of FCCS, Professor of the Department of Hospital Surgery of SUSMU; ORCID

Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery


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