Диастолическая дисфункция левого желудочка и прогноз у больных ишемической болезнью сердца с сердечной недостаточностью

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Abstract

For last decade prevalence of heart failure (HF) with normal left ventricular ejection fraction makes up to 54% in all HF cases. We have decided to scrutinize the problem of expansion of prognosis parameters search for patients with the Coronary Heart Disease (CHD) and HF. There were included 119 patients with CHD with II-IV HF functional classes (NYHA) in research. The group of comparison was made by patients with CHD without HF (n=162). Patients were observed during a half of a year. The survival rate of patients was estimated. Patients received the standard treatment. There were registered 10 (3.6%) deaths in group of patients with HF. With the help of the multifactorial analysis we have allocated 7 significant prognosis parameters: diastolic dysfunction of the left ventricular, Е/Е', diastolic pressure in pulmonary artery, pulmonary embolism, cachexia, quantitative changes of carotids, index of end systolic dimensions of the left ventricular. With the help of the equation of linear regress we have calculated three degrees of risk of fatal outcome with sensitivity of 81.8%, and specificity of 86.4%.

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Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, Director of Bakoulev National Medical Research Center for Cardiovascular Surgery