Factors which affect coronary artery bypass grafting outcomesin subjects with myocardial infarction

Authors: N.V. Kondrikova 1, V.N. Karetnikova 1,2, 2, S.V. Ivanov 1, A.V. Osokina 1, M.G. Zinets 1, R.A. Gayfulin 1

Company: 1 Research Institute for Complex Issues of Cardiovascular Diseases Siberian Branch of the Russian Academy of Sciences; Sosnovyy bul’var, 6, Kemerovo, 650002, Russian Federation;
2 Kemerovo State Medical Academy of Ministry of Health of the Russian Federation; ulitsa Voroshilova, 22a, Kemerovo, 650029, Russian Federation

Type:  Stable ischemic heart disease


DOI: https://doi.org/10.15275/kreatkard.2015.03.02

For citation: Kondrikova N.V., Karetnikova V.N., Ivanov S.V., et al. Factors which affect coronary artery bypass grafting outcomes in subjects with myocardial infarction. Creative Cardiology. 2015; 3:16-25 (in Russia)

Keywords: myocardial infarction coronary artery bypass grafting complications

Full text:  

 

Abstract

Purpose. To identify perioperative risk factors of coronary artery bypass grafting in subjects with myocardial infarction (MI) during hospital stay.

Material and methods. The study was conducted in 2008–2013 and enrolled 151 subjects with myocardial infarction who underwent coronary artery bypass grafting during the inpatient period of the index event treatment. The study endpoints were: death, cardiovascular, respiratory or other system complications in postoperative period, as well as postoperative wound complications during hospital stay.

Results. Univariate and multivariate analyses included following parameters for identifying predictors of adverse cardiovascular events during postoperative period: gender, age, MI localization, time before CABG performing, intra-aortic balloon counterpulsation, the number of bypassed arteries, type of imposed bypass graft, duration of extracorporeal circulation, EuroSCORE scale result and others. Univariate analysis revealed an increased probability of cardiovascular events in postoperative period when the total score by EuroSCORE scale is 6 or more (odds ratio (OR) 2,41; 95% confidence interval (CI) 1,18–4,92; р=0,015). Also we marked a tendency for reducing a risk of complications during hospital stay after vein graft utilization (р=0,056).

Conclusion. The independent risk factor of postoperative complications in MI patients after CABG was more than 6 points by EuroSCORE scale. Each single parameter of EuroSCORE scale had no significant influence on prognosis of adverse cardiovascular events of CABG in this group of patients.

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Chief Editor

Leo A. Bockeria, MD, PhD, DSc, Professor, Academician of Russian Academy of Sciences, President of Bakoulev National Medical Research Center for Cardiovascular Surgery